Origin and Development of Pop Art Essay Example | Topics and Well Written Essays - 750 words

Origin and Development of Pop Art - Essay Example Before the movement, people never thought that art was something that anyone could do. The movement, therefore, brought about a revolution in the West and the western culture went pop crazy within a few years. This work gave birth to realism in pop art. Hamilton developed his art from commercial art sources. This was a time when the influences of advertising and mass communication was setting an important stage in America there were numerous television stations and newspapers that were being published daily. In addition, movies and plays theatres were open at any hour of the day or night, and this served to encourage artists during the 1950s. Besides the visual arts, the Pop Art movement, from 1960s incorporated pop music, mainly rock and roll music. The initiation of this era was a result of the attempt of the US artists to borrow from blues to create a musical style that was impressive to the new movement and its related generation. In the 60s and 70s, the Pop Art development was faced by opposition from the community who found the rebellion of the teenagers as negative to the social structures. However, the gains by the music entrepreneurs and the artists’ promoters made the movement even more strong to the extent that it became relatively acceptable. However, it was still associated with the young and revolt generation that was out to gain independence from the family. This is due to the complete originality and freedom of innovation that has characterized the culture.

Autoimmunity and risk of cancet Essay Example | Topics and Well Written Essays - 1000 words

Autoimmunity and risk of cancet - Essay Example Discussion Stimulation of T-cell leads to maintained survival of T-cells when stimulated by self-protein MHC. Lymphoproliteration results if T-cell homeostasis is altered. Moreover, in certain circumstances, an interaction between activated T-cells and B-cells (e.g CD40L-CD40 interaction) may lead to autoimmunity (Rose & Mackay, 2006). Sometimes, the presence of self-antigen may become the cause of stimulation of T-cells; this activation is tolerated by phenomenon like anergy or deletion (Mak & Saunders, 2006). It therefore follows that failure to achieve deletion in this scenario may cause an autoimmune process to flourish. Moreover, defectively matured dendritic cells might interact with T-cells to generate a class to T-cells that are directed against self-antigens. Upon infection by a foreign pathogen, T-cells are activated and various clones are generated. Some of these clones can possibly cross-react with self-antigens resulting in transient or permanent autoimmunity (Ohashi, 20 02). In normal cells, the process of production of cells is tightly regulated by a number of very important mechanisms. Moreover, the new cells which are produced become differentiated and specialized to perform the function for which they are produced (Sherwood, 2012). This controlled multiplication of cells when becomes defective leads to the production of cells which are uncontrolled; cells start producing in an uncontrollable fashion. Therefore, due to this type of defective mitotic process, the cells that are produced are 'de-differentiated' and unable to perform their desired function. This results in a neoplasm. Neoplastic tissue demonstrates a growth rate that exceeds the growth rate of normal healthy tissue of the body (Stubblefield & O'Dell, 2009). For this reason, it manifests as a mass which is often referred to as a tumor. Since cancerous cells are not the exact replicas of the normal healthy cells of the body, they fail to mask themselves from the functioning immune sy stem of the body (Brunner & Smeltzer, 2010). Certain signals are 'flagged' on the cell membrane of cancerous cells that invite cells of the immune system to target such cells; therefore in most cases they are destroyed prior to the formation of their clone; cancerous cells are monoclonal in origin (Tobias et al, 2010). Inflammation brings about a number of changes to the vascular and epithelial tissues. Moreover, it affects the function of immune cells. This is the result of a complex interplay of molecules like cytokines, growth factors and chemokines (Jabbour et al, 2009). Furthermore, chronic inflammation due to irritation or infection has been accepted as a cause of cancer. Persistence of inflammation has been related to tumorigenesis and progression of cancer (Coussens & Werb, 2002). Tumor necrosis factor (TNF) plays a vital role in mediating inflammation by causing tissue destruction as well as recovery. The actions of TNF result in fibroblast growth which can destroy blood ve ssels and at the same time contribute to angiogenesis (Kollias et al, 1999). As far as the etiology of cervical cancer is concerned, the causative organism has been identified to be Human Papilloma Virus (HPV). Studies have shown that E6 and E7 oncogenes are incorporated into the genome of the host (Radosevich, 2012; Robertson, 2011; Stanley et al,

Philosophy Essays Platonic Epistemology Socratic

Philosophy Essays Platonic Epistemology Socratic Platonic epistemology seeks answers to key questions regarding the nature of reality, man, mind/soul, knowledge, being and becoming. The nature of this paper allows only the broadest brush strokes across the Platonic canvas. However following a brief introduction in which I will discuss the Socratic method and its influence on Platonic philosophy. Plato like his predecessor and mentor Socrates, aimed to identify the world around him using a more in depth methodology, from others that had been employed previously. The more Humanistic nature of Socratic enquiry was in marked contrast to the pre Socratic Naturalist approach. In The Republic Plato sets about an examination of specific concepts presented as a serious of dialogues or in a dialectic style. Through various metaphors and dialectic prose Plato delineates theories of reality (including the world of forms and being), the doctrine of Recollection, the roles of dialectic and aporia, and the tripartite structure theories of man and state. Benjamin Jowett in his edition of The Republic suggests the greater aim of Platos work is the â€Å"search after justice† embodying the fields of reality, man and knowledge discussed â€Å"On the basis of proverbial morality by Socrates and Polemarchus then caricatured by Thrasymachus reduced to an abstraction by Glaucon and Adeimantus† all based on the constructs of man and state as delineated by Socrates Influenced by his mentor Socrates and other Greek thinkers mentioned by Jowett. Platos work is still applicable today in a priori philosophies; Idealists concepts such as the tripartite nature of Man and State would have remarkable relevance in modern political theories including Utilitarianism and Communisms. Andrew Levine in his book Engaging Political Philosophy postulates: â€Å"Rousseaus investigation in The Social Contract was the realm of Platonic ideas or forms in contrast to the world of appearances, where de facto legitimate states exists† Any discussion on Platonic epistemology must inevitably weigh the influence of the Socratic school. Platos Socrates is the key to understanding the complexity of Platos thought. Socratic contrarianism and its methodology of aporia, a sort of constant intellectual [foundational] doubting, left Socrates free to claim that he was the wisest of men and was at the same time ‘wise in no way great or small. Platos later theories and epistemology would develop with Socrates almost rebellious dialectical style, questioning the accepted traditional beliefs of Greek intellectual society. (The historic Socrates stood trial and was sentenced to death for preaching his philosophy publicly; he refused to discontinue the practise) Platos adoption of Socratic contrarianism pervades much of his writings, especially in concepts as fundamentally abstract as his denial of knowledge through empirical observation; As witnessed in the Theaetetus when the Socratic midwife prepares to assist the young Theaetetus with his labours while delivering a reply to Socrates question â€Å"what is knowledge.† When questioned Theaetetus equates knowledge with perception, after intense dialectical questioning, during which Socrates successfully refutes arguments that perception is (biconditional) knowledge Theaetetus finally agrees, (with restrictions) that perception is not knowledge. So commences the search for an answer to the question Socrates asks, â€Å" what is knowledge?† Plato rejected all empirical claims to understand the true nature of knowledge â€Å" Knowledge is not constituted by sense impressions, but by the inferences we make about them, by that means being and truth are attainable, in the other way it is impossible† In the Theaetetus Plato demonstrates the concept of being as â€Å"fundamental and universal† Socrates points to the specialization of bodily sense organs. If we ask which organs enable us to formulate opinions or judgements that range across more than one field of sense-experience, we cannot identify such a grouping. â€Å"the things you perceive by means of another for example, that objects of hearing can not be objects of the seeing and vice versa?† The possession of mathematical knowledge or the ability to formulate judgements does not reside in some empirical â€Å" Sorting office†, Socrates states in the Meno, â€Å"Then knowledge is related to what is and knows what is and is as it is. The objects of mind are eternal; those of the senses always changing. Knowledge never changes; opinion, which is not tied down, is subject to change.† It now seems clear that what the mind knows is being, that which is eternal and unchanging, while the senses inform us concerning the â€Å"intermediate flux† The realm of being is comprised of ideas or forms and that of becoming by changing things. â€Å"Aporia and refutative cross examination serve to purify ambiguous formulation by excluding false and misleading interpretations and opening the path to true ones† reflects Rosemary Desjardins, in Logos in Platos Theatetus. Platos dialogues may indeed be aporetic but by subjecting both his interlocutors and readers to elenchus and meiutic method he hopes to lead from gross perceptibility to finer cognition. The relentless inquisitiveness of the Socratic method in conjunction with aporia lends to a degree of abstraction in the nature of Platos philosophy (referred to in Jowetts introduction to The Republic) evidenced by the allegory of the cave, the doctrine of recollection, the nature of reality, the concept of the divided line, and the theory of forms. The allegory of the cave allowed Plato to postulate several ideas archetypal of Platonic philosophy. The allegory of the cave describes the limit placed on mankind, by an over reliance on sensory perception, and the subsequent systems of knowledge that relied on empirical evidence alone to deduct truths. For Plato, the resultant effect of mans self-shackling (empirical observation) is described in Book VII of The Republic. Plato views mankind as: â€Å"living in a underground [den] which has its mouth open towards the light and reaching all along the den; here they have been from their childhood, and have their legs and neck chained so that they cannot move, and can only see before them, being prevented by the chains from turning round their heads† Plato does not give a finite explanation of enlightenments form nor does he give an example of reality, what he demonstrates in the allegory of the cave is a clear method or path, that man and society must pursue to achieve deeper knowledge of reality. Like the prisoners emergence from the cave, enlightenment at first will be difficult to understand, like the temporary blindness they suffer when first exposed to sunlight, its an arduous path that takes time, patience, temperance and practice, with the temptation for a return to former ignorance always present. Ignorance when lifted will deliver us into the Real world of philosophy with man finally comprehending his own place on the path to true knowledge. Plato delineates this movement with mathematics through the image of a straight line. He divides this imaginary line into two unequal segments, the large segment represents the intelligible world, and the smaller the visible world. He further divides these segments in the same ratio as his first division. The division in the larger segment represents the world of higher and lower forms (ideas). The division in the visible world represent visible objects and the lowest segment represents their shadows and reflections (imagination). For Plato the line represents the levels of cognition available to man and society. Socrates avowed mission was to educate the Athenian populace up until the last days of his life. He likened his mission to that of a gadfly, ‘stinging the lethargic Athenian horse into wakefulness through the application of philosophical dialectic (Socratic method) Plato believed if entered into in good faith, this method would ensure a cognitive assent along the divided line. He believed until individuals and society, collectively questioned the political, ethical, and moral status quo, conciousness would remain in bondage much like the prisoners restricted mechanical life in the cave. Answering his critics regarding the phenomenon of knowledge Plato states that the soul is immortal â€Å" the soul, since it is immortal, and has been born many times, and seen all things both here and in the other world, has learned every thing that is† Plato offers proof of the souls immortality, in the Phaedrus he postulates that its the nature of the soul to initiate its own changes, in effect to be self moving, rather than moved by an outside agency. Therefore the soul cannot be destroyed nor can it come into being. ‘It was not, nor will be, but always is, one whole continuum. (Parmenides.) To contemporary ears the Platonic soul bears great similarities to the Christian Soul unlike his Doctrine of Recollection or anamnesis; Platos Socrates denies his own wisdom; in the Apology he states, â€Å" human wisdom is worth little or nothing† he merely asserts that he is a â€Å" midwife† assisting in the â€Å"rebirth† of knowledge lying dormant in the mind Opinions proven wrong in the course Socratic investigation, does not demonstrate lack of knowledge, but rather, the clouding of mind on account of sensory perception. Platos Socrates asserts that dialectical investigation (with its constant questioning) would lead the inquiring mind towards clues, allowing it a recollection of what was already known through the many cycles of rebirth. Although considered a Platonic absolute the Doctrine of Recollection cannot be contested or proved. Platonic abstraction, denies legitimate validity to Empirical investigation. The a priori solution given by the slave boy in the Meno to the mathematical question posed by Socrates, hardly resolves this problem. Tying into the Doctrine of Recollection and the minds compromised judgement on account of sensory perception, Platos Theory of forms plays a greater role in the Allegory of the cave, where the impressions cast on the caves wall are believed to be real. For Plato the shadows on the wall were a reflection of empirical reality, which in turn was a reflection of a Reality whos dwelling lay in the realm of Forms (ideas). Platos theory of Forms is base on the notion that all things in the world share in common with a greater abstract (ideas) that in turn embodies all things in the empirical world. For example a small red chair, sharing certain physical characteristics in common with a large white chair, is not a real chair, but the perception of the abstract â€Å"chair† in which the white chair and all other chairs mimic. Plato translated his notion of the intangible into the Tripartite nature of man; man Plato contended, was comprised of physical material (the body), and the abstract immaterial (soul and mind). While co-dependant, the two parts ¾ matter and form ¾, function separately of each other.

Interpretation on Scientific Article about Sense of Smell Essay example

Introduction The sense of smell is what informs an organism of the chemical composition of their surrounding environment. The sense of smell is called olfaction and in humans, it is less developed than in most other mammals. The olfactory system contains epithelial cells that are unique because they are capable of regeneration, unlike most other neurons. The receptors for both taste and smell are called chemoreceptors. They are termed chemoreceptors because they respond to chemicals that are in aqueous solution. The olfactory epithelium is what allows us to smell; it is located in the roof of the nasal cavity and contains millions of sensory neurons. It is a patch and contains approximately 50 million sensory receptor cells. The receptor cells being referred to are actually neurons. The olfactory epithelium is comprised of three different layers, which include supporting cells, olfactory receptor cells, and basal cells. Supporting cells aid in the production of mucous and they support the olfactory receptor cells. The basal cells are at the base of the epithelium and they are the source of newly developed receptors. Tiny hair like structures, called cilia, are found on the olfactory receptors and they are covered with mucous. If molecules entering the nostrils dissolve in the mucous, they stimulate the receptors and the sense of smell is evoked. The substances that can be smelled have to be able to evaporate at normal temperatures and should be fairly water soluble so they can pass through t he mucous. The molecules should also be lipid soluble because the cilia are composed of lipids. A mature sensory neuron is a bipolar neuron, meaning it has two poles, or ends. The neuron receives signals through a branch known as a dendri... ... but quite possibly most important, much research is being conducted involving the degeneration of the olfactory system. One of the first signs of Alzheimer's disease is the loss of smell. By understanding the plasticity of the receptors in the olfactory system, there may be a way to further understand why degeneration takes place and how it could be treated. The future of this science is far reaching and combined with gene expression, it will become a heated topic. There are exciting discoveries taking place, such as the odorant receptors in sperm and even products in the material world. The olfactory system should provide a long future of discoveries due to the intricacies of its circuitry and the vast network it encompasses. References Momberts. Nature. "Putting Smell on the Map". Volume 419. pg. 296-300. 19 Sept. 2002. 2002 Nature Publishing Group.

Career Interest Profiler

The results from my interest profiler were enterprising occupations, social occupations and conventional occupations. Enterprising occupations include starting up and carrying out projects. These occupations can involve leading people and making many decisions. Sometimes they require risk taking and often deal with business. Social occupations frequently involve working with, communicating with, and teaching people. These occupations often involve helping or providing service to thers and conventional occupations frequently involve following set procedures and routines.These occupations can include working with data and details more than with ideas. Usually there is a clear line of authority to follow. The results of my competencies were organizing, strategizing, innovating, following instructions, adapting to change and entrepreneurial thinking. As stated in my career plan a lawyer, Judge, supervisor of an office, administrative support worker, upervisor of protective service worker s and supervisor of sales workers were examples of possible Job titles that matched my competencies.According to my career plan the first result of my work culture preferences was supportive which includes a secure, stable environment, clearly defined Jobs, goals and expectations, no conflicting demands, considerate management, focuses on employee welfare, lots of personal development and feedback, lots of recognition and celebration of success and a fun place to work.The second result was high powered which includes demanding Jobs, career development, career advancement, the chance to learn new skills, the chance to try different Jobs or work in different places, high salaries, likelihood of rapid promotion and other benefits. Last, but not least the third result was ethical which includes emphasis on fairness, active promotion of equal rights and Justice for all, the chance to contribute positively to society and make a difference to people's lives and an emphasis on social and en vironmental esponsibility.After taking the assessments for my career interest profiler, competencies and work culture preferences, I have gained a lot of useful information about myself as well as in regards to what specific characteristics I possess and what type of employment opportunities I should be searching for. There was a ton of information to consider after looking at the results, but I feel as though I can take this information and apply it to my life as I am looking to advance within my career.

Andrew Grove

Intel Corporation is one of the world leaders in terms of microchip and microprocessor production. They embark on a mission of staying in the top and even formulated a strategy on exploring other forms of markets like that of digital health and wireless applications. They have also been known to forge tie-ups with leaders of the prospective markets they are exploring. They have tied up with search engine Google for the wireless application as an example. Basically, Intel operations are divided into two sections: the communications group, known as ICG or Intel Communications Group; and the other section consists of the Intel Architectural business. The architectural section is responsible for the production of â€Å"platform† boards that consists of chipsets and microchips, which are used in desktop processors; including the Intel Pentium 4 processor and the Celeron. On the other hand, the communications section deal mostly with the production and development of wireless technology. They are mostly concerned with flash memory and cellular base-band technology. Intel is also known for large-scale tie-ups with other firms. Example of such is their tie-up with search engine Google for development of wireless technologies. They are also know to be connected with other firms like Microsoft and Dell. However, competition has been seen to catch up on the leadership oh Intel. Recently, a lot of clamors have been heard in the recent decision of present CEO Paul Otellini unveiled his plan to ship the micro-chip corporation to another industry. While the rest had their problems with it, former CEO Andrew Grove is all praises for it. The present CEO’s vision is to generally change the image of Intel starting from what Andrew Grove practically built. Starting from the scrapping of the famous â€Å"e† trademark of the logo, the company motto and even the brand, the company has been envisioned to undergo a transformation. A lot of managers seem to be against the changing of such things that made Intel a household name. Even the logo has been widely known in all parts of the globe. Meanwhile, Andrew Grove has been vocal about his approval of the said changes. In his opinion, they are of the same line of thinking that the present CEO has, that the company really has to undergo these changes in order for the to tell the world that even Intel is adjusting to the fast-paced growth of the industry and that they, as a company, should be at equal footing with the rest of the companies in the same industry.   He further stresses that it is a imperative for the company to show that the company exhibits a show of risk-taking and result orientation, accompanied also by the value of discipline. Before, under Grove’s supervision and Craig Barrett (Grove’s successor), the company focused on the production of microprocessors and took the lead in that industry for years. They helped give birth to the Information Age by producing more microchips and therefore, producing faster computers and ending in the development of micro processing. However, what Otellini had in mind is far from the former image of Intel, considering that he even wanted to change the logo and company symbol. He wanted to venture into uncharted regions of digital health industry and that of â€Å"platform† inventions. Despite the negative views about Otellini’s decision, Analysts from outside the company have cited other views about the subject, stating the fact that sometimes, change is needed for a big company to maintain solid advantage. They also added that other companies that survived the changes maintained industry leadership, just like what happened to Texas Instruments. However, the other side notes that it is not really that advisable to change their target industry and find a niche in other markets, although they have leadership in the industry they would leave. Adding firepower to the firepower of the critics, Intel’s competitor, AMD (Advanced Micro Devices) Inc., have scored a major point against Intel as it topped the company in terms of consumption as AMD Inc rose to a higher percentage in 2003 and analysts view that it would continue to rise against Intel unless Intel releases a new competitive line of processors in the future.. In the wireless communications field, Texas Instruments and Qualcomm Inc are still standing their own ground against Intel’s advances. Also, the two companies are planning to release their own versions of the platform that they assured, would gain more shares of the market than the new Intel is trying to build a niche on. On the other hand, many people are applauding Otellini’s vision of the new Intel, stating that they have never seen so much innovation in technology with respect to their fields, especially that of medicine. Also, people have actually seen the growth of the company, showing promise for a whole variety of new plans that are underway. Not only did the plans boost company ties with other companies, but also made their partner companies believe in the new flexibility of Intel. They promoted closer ties with cellular phone conglomerates Nokia and Samsung; had present tie-ups with Google; ties with Sony and Philips; and with those ties, Intel was able to produce and release different types of innovative products. There different developments have different market reactions. Some producing great results, others not. However, analysts are right in pointing out that other companies that are industry leaders also experienced changes that looked like they are headed nowhere, although in the end, they have proven that their change would actually pay off. And now, Intel took their lead and eventually took some changes in themselves as well. The problem would be, if they can maintain the positive effects and eliminate the negative effects of the changes. As for their decision of making the company over, It is. The industry’s reaction to it seemed to treat the decision as a smart move as well. Rival AMD Inc made some deals with ATI, and this showed that Intel produced a bigger threat than before. Also, the result of other marketing strategies in the release of the new products proved that Intel can really hold its own against the rivals in the industries that they have entered. They also showed that they can maintain the leadership in their industry, and even remodeled themselves into a more serious threat than that of before. However, not all decisions solely produce good effects. The negative effects therefore should be dealt with accordingly. Otellini did not make a bad move and he assured that he would produce good results which he did, although in the process nearly humiliating the company as he suffered near losses and continue to be behind Texas Instrument in the other fields. Intel not only made a good decision externally but also made breakthrough decisions internally, taking care of their employees better and giving chances to other fields like medicine to be at the same level as that of the engineers, the firepower of Intel before. May be this was a factor in Otellini’s equation that he devised for company growth. All in all, Intel has made a remarkable shift from the way it was thirty seven years ago. It also departed from the household figure that we recognized. Although this a bold move in there part and a rather risky one considering the old model is one of the main reasons why Intel made it to the top. In Otellini’s, and now Intel’s belief, It is one risky move that was designed to maintain leadership and gain advantages in other fields that they would pursue in the future. The market and business world would have to look out as Intel’s new look is bound to stay, and so is their new outlook in the business battles. BIBLIOGRAPHIES Intel Corp. Company Profile. Yahoo! Finance. Retrieved October 26, 2006. (http://biz.yahoo.com/ic/13/13787.html) Intel Corporation. Computer Business Review Online. Retrieved October 26, 2006. (http://www.cbronline.com/companyprofile.asp?guid=E82C088A-0488-4DB5-8953-9E316C2B44D1&CType=Background)